MCAT Organic Chemistry Question 145: Answer and Explanation

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Question: 145

10. Each of the following reaction types occurs during the Gabriel synthesis EXCEPT:

  • A. decarboxylation.
  • B. nucleophilic substitution.
  • C. dehydration.
  • D. hydrolysis.

Correct Answer: C

Explanation:

The Gabriel synthesis includes two nucleophilic substitution steps, followed by hydrolysis and decarboxylation. Dehydration—the loss of a water molecule—is not a part of this reaction.

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