MCAT Organic Chemistry Question 144: Answer and Explanation
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Question: 144
9. During the Gabriel synthesis, phthalimide serves as the:
- A. nucleophile.
- B. base.
- C. leaving group.
- D. electrophile.
Correct Answer: A
Explanation:
During the Gabriel synthesis, phthalimide attacks a secondary carbon in diethyl bromomalonate. The secondary carbon is the electrophile, choice (D), and bromide is the leaving group, choice (C).