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1. An experimenter is attempting to investigate the effect of a new antibiotic on E. coli. He plates cells and administers one milliliter of the antibiotic. Which of the following is an appropriate negative control in this experiment?
2. Which of the following would best establish a causal link?
3. An experimenter is attempting to determine the internal energy of a well-known compound He cleans his glassware, completes the synthesis, calibrates a bomb calorimeter, and then uses it to measure the appropriate thermodynamic values. Which of the following errors did he make?
4. A researcher wishes to generate a parameter for American women's mean weight. Which of the following is the most significant concern?
5. A cross-sectional study in which current smoking status and cancer history are assessed simultaneously cannot satisfy which of Hill's criteria?
6. After randomization, it is discovered that one group in a study has almost twice as many women as the other. Which of the following is an appropriate response?
7. An experimenter is attempting to determine the effects of smoking on very low birth weight (VLBW) and of VLBW on IQ. Which of the following statements is correct?
Smoking is an independent variable.
Smoking is a dependent variable.
VLBW is an independent variable.
VLBW is a dependent variable.
8. A study is performed on a new medication. Subjects in the experimental group are told about the potential side effects of the medication, while subjects in the placebo group are not. The subjects have no contact with each other and do not know in which group they are placed. The side effects end up being significantly more severe in the treatment group, when seen by the same assessor physician. This is most likely caused by which of the following?
9. Which of the following relationships between measurement error and overall error is correct?
10. A new study of a weight loss drug uses a radio advertisement to generate study participation. What type of error is most likely to result?
11. A researcher designing a study has paid for it to be professionally translated into several languages. She discusses the potential risks and benefits with each participant and allows them to bring documentation home for review before committing to the study. This researcher has put special focus on:
12. Which of the following methods would be most appropriate for an initial assessment of hemoglobin saturation during an experiment about breath holding?
13. A medical student attempting to impress her attending physician refers to a recent article that says that there is a statistically significant difference in pregnancy length with a new therapy. Which of the following is most likely to be a valid criticism of the article?
14. Which sample would be the most appropriate participants for a study on hormone replacement therapy for postmenopausal symptoms?
15. Use of a colorimetric assay to determine protein concentration may be subject to all of the following EXCEPT:
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