MCAT Biology Question 39: Answer and Explanation

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Question: 39

9. Which of the following is FALSE with regard to adult stem cells?

  • A. They retain inherent pluripotency if harvested from selected organs.
  • B. They are less controversial than embryonic stem cells.
  • C. They require treatment with various transcription factors.
  • D. There is a reduced risk of rejection if patient's own stem cells are used.

Correct Answer: A

Explanation:

Embryonic stem cells are controversial because they require destruction of an embryo to harvest, eliminating choice (B). Adult stem cells are significantly less controversial, but require treatment with various transcription factors in order to induce an increased level of potency, eliminating choice (C). Rejection is a concern when foreign cells are introduced into an individual; using one's own stem cells should remove this risk, eliminating choice (D). Adult stem cells are not naturally pluripotent, unless pluripotency has been induced by strategic use of transcription factors. Therefore, choice (A) is the correct answer.

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