MCAT Biochemistry Question 54: Answer and Explanation
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Question: 54
9. Why is the α-anomer of d-glucose less likely to form than the β-anomer?
- A. The β-anomer is preferred for metabolism.
- B. The β-anomer undergoes less electron repulsion.
- C. The α-anomer is the more stable anomer.
- D. The α-anomer forms more in l-glucose.
Correct Answer: B
Explanation:
The hydroxyl group on the anomeric carbon of the β-anomer is equatorial, thereby creating less steric hindrance than the α-anomer, which has the hydroxyl group of the anomeric carbon in axial position.