MCAT Biochemistry Question 29: Answer and Explanation

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Question: 29

14. Which of the following is LEAST likely to be required for a series of metabolic reactions?

  • A. Triglyceride acting as a coenzyme
  • B. Oxidoreductase enzymes
  • C. Magnesium acting as a cofactor
  • D. Transferase enzymes

Correct Answer: A

Explanation:

Triglycerides are unlikely to act as coenzymes for a few reasons, including their large size, neutral charge, and ubiquity in cells. Cofactors and coenzymes tend to be small in size, such as metal ions like choice (C) or small organic molecules. They can usually carry a charge by ionization, protonation, or deprotonation. Finally, they are usually in low, tightly regulated concentrations within cells. Metabolic pathways would be expected to include both oxidation–reduction reactions and movement of functional groups, thus eliminating choices (B) and (D).

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