MCAT Biochemistry Question 178: Answer and Explanation
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Question: 178
13. Which of the following side effects would be anticipated in someone taking leptin to promote weight loss?
- A. Drowsiness
- B. Increased appetite
- C. Irritability
- D. Fever
Correct Answer: A
Explanation:
Leptin acts to decrease appetite by inhibiting the production of orexin. Orexin is also associated with alertness, so decreasing the level of orexin in the body is expected to cause drowsiness. Even without this information, the answer should be apparent because the body tends to maintain an energy balance. If consumption decreases, energy expenditures are expected to decrease as well.