MCAT Biochemistry Question 134: Answer and Explanation
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Question: 134
14. Which of the following is/are function(s) of NADPH in the cell?
I. Antimicrobial resistance via bacterial destruction by bleach within lysosomes.
II. Involvement in the production of the precursors to steroid hormones.
III. Functional carriage of energy across organelle membranes for use within the mitochondria
- A. I only
- B. I and II only
- C. II and III only
- D. I, II, and III
Correct Answer: B
Explanation:
NADPH has three primary functions: involvement in biosynthesis of lipids and cholesterol (the precursor to steroid hormones), production of bactericidal bleach in the lysosomes of certain white blood cells, and maintenance of a supply of reduced glutathione for protection against free radical damage. Energy carriage is an important function of NADH, not NADPH.