MCAT Organic Chemistry Question 141: Answer and Explanation
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Question: 141
6. A biochemist is synthesizing valine, shown below, using the Strecker synthesis. Which of the following carbonyl-containing compounds would be an appropriate starting reactant in this synthesis?
- A. 2-Propanone
- B. Propanal
- C. 2-Methylpropanal
- D. Butanal
Correct Answer: C
Explanation:
The Strecker synthesis creates an amino acid from an aldehyde. The carbonyl carbon ultimately becomes the α-carbon of the amino acid. Any remaining alkyl chain becomes the R group, as shown below. The starting compound is therefore 2-methylpropanal (isobutyraldehyde).
