MCAT Biology Question 20: Answer and Explanation
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Question: 20
5. Certain ovarian tumors called granulosa cell tumors are known to produce excessive levels of estrogen. A physician who diagnoses a granulosa cell tumor should look for a secondary cancer in which of the following parts of the reproductive tract?
- A. Fallopian tube
- B. Cervix
- C. Endometrium
- D. Vagina
Correct Answer: C
Explanation:
Estrogen is known to cause growth of the endometrial lining during the follicular phase of the menstrual cycle, and its levels stay high during the luteal phase to promote vascularization and glandularization of this tissue. Excessive levels of estrogen may provide a strong enough signal for cell growth to promote tumor formation, or even cancer. The other tissues listed in this question require estrogen for development, but are not strongly associated with rapid tissue growth due to estrogen.