MCAT Biology Question 150: Answer and Explanation
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Question: 150
15. Sarin is a potent organophosphate that can be used in chemical warfare. As an inhibitor of acetylcholinesterase, sarin causes excessive buildup of acetylcholine in all synapses where it is the neurotransmitter. Which of the following symptoms would be most likely to be seen in an individual with sarin poisoning?
- A. Increased urination and increased sweating
- B. Increased urination and decreased sweating
- C. Decreased urination and increased sweating
- D. Decreased urination and decreased sweating
Correct Answer: A
Explanation:
An excess of acetylcholine will lead to activation of all parasympathetic neurons, preganglionic sympathetic neurons, and the postganglionic sympathetic neurons that innervate sweat glands. Because the parasympathetic nervous system causes contractions of the bladder, one would expect increased urination. The increased activation of sweat glands would lead to increased sweating as well.