MCAT Biology Question 149: Answer and Explanation

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Question: 149

14. A drug is used that prevents the conversion of angiotensin I to angiotensin II. What is a likely effect of this drug?

  • A. Increased sodium reabsorption
  • B. Increased potassium reabsorption
  • C. Increased blood pressure
  • D. Increased blood pH

Correct Answer: B

Explanation:

Normally, angiotensin II causes secretion of aldosterone from the adrenal cortex. Aldosterone serves to increase reabsorption of sodium, while promoting excretion of potassium and hydrogen ions. Thus, blocking the release of aldosterone should result in decreased reabsorption of sodium, while decreasing excretion of potassium and hydrogen ions. This eliminates choices (A) and (D) and makes choice (B) the correct answer. In the absence of aldosterone, less water reabsorption will occur, eliminating choice (C).

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