MCAT Biology Question 106: Answer and Explanation

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Question: 106

1. In DiGeorge syndrome, the thymus can be completely absent. The absence of the thymus would leave an individual unable to mount specific defenses against which of the following types of pathogens?

  • A. Viruses
  • B. Bacteria
  • C. Parasites
  • D. Fungi

Correct Answer: A

Explanation:

T-lymphocytes, which mature in the thymus, are the only specific defense against intracellular pathogens. While some bacteria, fungi, and parasites can live intracellularly, viruses—by definition—must replicate within cells. The absence of T-cells would leave an individual unable to fight viral infections with specific defenses.

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