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1. During a myocardial infarction, the oxygen supply to an area of the heart is dramatically reduced, forcing the cardiac myocytes to switch to anaerobic metabolism. Under these conditions, which of the following enzymes would be activated by increased levels of intracellular AMP?
2. A patient has been exposed to a toxic compound that increases the permeability of mitochondrial membranes to protons. Which of the following metabolic changes would be expected in this patient?
3. Which of the following INCORRECTLY pairs a metabolic process with its site of occurrence?
4. Which of the following processes has the following net reaction?
2 acetyl-CoA + 6 NAD+ + 2 FAD + 2 GDP + 2 Pi + 6 H2O → 4 CO2 + 6 NADH + 2 FADH2 + 2 GTP + 6 H+ + 2 CoA–SH
5. In glucose degradation under aerobic conditions:
6. Fatty acids enter the catabolic pathway in the form of:
7. In which of the following reactions is the reactant oxidized?
8. In which part of the cell is cytochrome c located?
9. Which of the following correctly shows the amount of ATP produced from the given high-energy carriers?
10. Why is it preferable to cleave thioester links rather than typical ester links in aerobic metabolism?
11. Which enzyme converts GDP to GTP?
12. Which of the following best explains why cytosolic NADH can yield potentially less ATP than mitochondrial NADH?
13. In high doses, aspirin functions as a mitochondrial uncoupler. How would this affect glycogen stores?
14. Which complex does not contribute to the proton-motive force?
15. Which of the following directly provides the energy needed to form ATP in the mitochondrion?
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