MCAT Biochemistry Question 93: Answer and Explanation
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Question: 93
3. Topoisomerases are enzymes involved in:
- A. DNA replication and transcription.
- B. posttranscriptional processing.
- C. RNA synthesis and translation.
- D. posttranslational processing.
Correct Answer: A
Explanation:
Topoisomerases, such as DNA gyrase, are involved in DNA replication and mRNA synthesis (transcription). DNA gyrase is a type of topoisomerase that enhances the action of helicase enzymes by the introduction of negative supercoils into the DNA molecule. These negative supercoils facilitate DNA replication by keeping the strands separated and untangled.