MCAT Biochemistry Question 19: Answer and Explanation

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Question: 19

4. Which of the following factors determine an enzyme's specificity?

  • A. The three-dimensional shape of the active site
  • B. The Michaelis constant
  • C. The type of cofactor required for the enzyme to be active
  • D. The prosthetic group on the enzyme

Correct Answer: A

Explanation:

An enzyme’s specificity is determined by the three dimensional shape of its active site. Regardless of which explanation for enzyme specificity we are discussing (lock and key or induced fit), the active site determines which substrate the enzyme will react with.

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