MCAT Biochemistry Question 176: Answer and Explanation

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Test Information

Question: 176

11. In the absence of oxygen, which tissue will experience damage most rapidly?

  • A. Skin
  • B. Brain
  • C. Red blood cells
  • D. Liver

Correct Answer: B

Explanation:

The brain uses aerobic metabolism of glucose exclusively and therefore is very sensitive to oxygen levels. The extremely high oxygen requirement of the brain (20% of the body’s oxygen content) relative to its size (2% of total body weight) implies that brain is the most sensitive organ to oxygen deprivation.

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