MCAT Biochemistry Question 173: Answer and Explanation

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Question: 173

8. How do hormonal controls of glycogen metabolism differ from allosteric controls?

  • A. Hormonal control is systemic and covalent.
  • B. Hormonal control is local and covalent.
  • C. Hormonal control is systemic and noncovalent.
  • D. Hormonal control is local and noncovalent.

Correct Answer: A

Explanation:

Hormonal controls are coordinated to regulate the metabolic activity of the entire organism, while allosteric controls can be local or systemic. The modification of the enzymes of glycogen metabolism by insulin and glucagon is either through phosphorylation or dephosphorylation, both of which modify covalent bonds.

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