MCAT Biochemistry Question 163: Answer and Explanation
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Question: 163
13. Which of the following is true regarding ketolysis?
- A. Ketolysis occurs only in the brain.
- B. Ketolysis occurs in the liver.
- C. Ketolysis generates acetyl-CoA.
- D. Ketolysis increases glucose metabolism.
Correct Answer: C
Explanation:
Ketolysis is the breakdown of ketone bodies to acetyl-CoA for energy. This process occurs in the brain and muscle tissues, but cannot occur in the liver, which lacks an enzyme necessary for ketone body breakdown. Ketolysis is not associated with an increase in glucose metabolism because it most often occurs under conditions of starvation.