MCAT Biochemistry Question 156: Answer and Explanation
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Question: 156
6. Statin drugs inhibit HMG-CoA reductase. As such, they are likely prescribed for:
- A. hypercholesterolemia (high cholesterol).
- B. hypertriglyceridemia (high triacylglycerol).
- C. hypocholesterolemia (low cholesterol).
- D. visceral adiposity (obesity).
Correct Answer: A
Explanation:
Statins are drugs that are prescribed to treat high cholesterol and act as competitive inhibitors of HMG-CoA reductase. HMG-CoA reductase is the rate-limiting enzyme of de novo cholesterol synthesis; inhibition of this enzyme lowers production of cholesterol, thus lowering overall levels of cholesterol.