MCAT Biochemistry Question 155: Answer and Explanation
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Question: 155
5. Which of the following could result from an absence of apolipoproteins?
I. An inability to secrete lipid transport lipoproteins.
II. An inability to endocytose lipoproteins.
III. A decreased ability to remove excess cholesterol from blood vessels.
- A. I only
- B. III only
- C. I and II only
- D. I, II, and III
Correct Answer: D
Explanation:
While the transport and lipid binding functions of most lipoproteins are independent of the apolipoprotein component, the interaction of these lipoproteins with the environment is controlled almost exclusively by apolipoproteins. Lipoproteins cannot exit or enter cells without apolipoproteins, and are unable to transfer lipids without specialized apolipoproteins or cholesterol-specific enzymes.