MCAT Biochemistry Question 153: Answer and Explanation

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Question: 153

3. During fatty acid mobilization, which of the following occur(s)?

I. HSL is activated.

II. Free fatty acids are released.

III. Gluconeogenesis proceeds in adipocytes.

  • A. I only
  • B. III only
  • C. I and II only
  • D. II and III only

Correct Answer: C

Explanation:

During fatty acid mobilization, there is a breakdown of triacylglycerols in adipocytes by hormone-sensitive lipase (HSL). This breakdown results in the release of three fatty acids and a glycerol molecule. The glycerol may be used by the liver for gluconeogenesis, but adipocytes do not have the ability to carry out gluconeogenesis.

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