MCAT Biochemistry Question 15: Answer and Explanation

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Question: 15

15. Collagen consists of three helices with carbon backbones that are tightly wrapped around one another in a "triple helix." Which of these amino acids is most likely to be found in the highest concentration in collagen?

  • A. Proline
  • B. Glycine
  • C. Threonine
  • D. Cysteine

Correct Answer: B

Explanation:

Because collagen has a triple helix, the carbon backbones are very close together. Thus, steric hindrance is a potential problem. To reduce that hindrance, we need small side chains; glycine has the smallest side chain of all: a hydrogen atom.

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