MCAT Biochemistry Question 138: Answer and Explanation

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Question: 138

3. Which of the following INCORRECTLY pairs a metabolic process with its site of occurrence?

  • A. Glycolysis—cytosol
  • B. Citric acid cycle—outer mitochondrial membrane
  • C. ATP phosphorylation—cytosol and mitochondria
  • D. Electron transport chain—inner mitochondrial membrane

Correct Answer: B

Explanation:

The citric acid cycle takes place in the mitochondrial matrix, not the outer mitochondrial membrane. While most citric acid cycle enzymes are located within the matrix, succinate dehydrogenase is located on the inner mitochondrial membrane.

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