MCAT Biochemistry Question 122: Answer and Explanation

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Question: 122

2. Which of the following organs does NOT require a constant supply of glucose from the blood for energy during a fast?

  • A. Red blood cells
  • B. Brain
  • C. Pancreas
  • D. Liver

Correct Answer: D

Explanation:

The liver, like all cells, needs a constant supply of glucose; however, it is able to produce its own glucose through gluconeogenesis (cells in the kidney can also complete low levels of gluconeogenesis). The other cells listed here are absolutely dependent on a glucose source from the blood for energy, although they may also use other fuels in addition to glucose. For example, the brain can utilize ketone bodies during lengthy periods of starvation; however, it still requires at least some glucose for proper function.

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